This new approach can give you vitamin D

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The “vitamin sun“also known as Vitamin D can be hard to find during the pandemic, when most people prefer to stay indoors. However, going out for some sun or getting a supplement may be a smarter choice.

But for some people with fat malabsorption syndromes, including those who have had gastric bypass surgery and those who are obese, may have trouble digesting or absorbing it.

For this reason, these people are at higher risk for osteoporosis and osteomalacia (softening of the bones).

Now, a new study, published in the American Journal of Clinical Nutrition, claims that 25-hydroxyvitamin D3 could be an effective treatment for people who are deficient in vitamin D and are unable to digest or absorb it through sunlight or general supplements.

Obese patients are also susceptible to vitamin D deficiency because vitamin D derived from intestinal absorption and skin synthesis is diluted in a larger mass of body fat.

According to the team, about a third of adults are obese and need much larger doses of vitamin D to meet their needs.

This vitamin D metabolite is better absorbed in patients with fat malabsorption syndromes and, since it is not as fat soluble, it does not dilute in body fat and is effective in increasing and maintaining blood levels of 25-hydroxyvitamin D in obese people.

explained corresponding author Michael F. Holick.

Healthy individuals, adults with fat malabsorption syndrome and obese adults were compared to assess whether a more water soluble form of vitamin D3 known as 25-hydroxyvitamin D3 was more effective. than the same dose of vitamin D3 to improve their vitamin D status.

The researchers observed that, compared to healthy adults, only about 36% of the vitamin D3 ingested orally was found in the blood of patients with fat malabsorption syndromes, including patients who had gastric bypass surgery. .

When the same adults ingested 25-hydroxyvitamin D3, patients with fat malabsorption syndromes were able to absorb it as well as healthy adults, thereby increasing their vitamin D status to the same degree. A similar observation was made in obese subjects compared to healthy controls.

Therefore, the use of 25-hydroxyvitamin D3 could be a new approach to treat vitamin D deficiency in patients with fat malabsorption syndromes and obese adults.

Holick added.

Vitamin D deficiency not only leads to bone loss increasing the risk of fracture, but leads to painful osteomalacia in the bones. Patients with vitamin D deficiency who suffer from osteomalacia have persistent pain in the bones and muscles.

Vitamin D deficiency has been linked to an increased risk of many chronic diseases, including multiple sclerosis, type 1 diabetes, heart disease, type 2 diabetes, depression, neurocognitive dysfunction, and disease. Alzheimer’s as well as infectious diseases, including COVID.

Image Credit: Getty

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